Subgrouping the autism "spectrum": reflections on DSM-5

PLoS Biol. 2013;11(4):e1001544. doi: 10.1371/journal.pbio.1001544. Epub 2013 Apr 23.


DSM-5 has moved autism from the level of subgroups ("apples and oranges") to the prototypical level ("fruit"). But making progress in research, and ultimately improving clinical practice, will require identifying subgroups within the autism spectrum.

Publication types

  • Research Support, Non-U.S. Gov't

MeSH terms

  • Child
  • Child Development Disorders, Pervasive / classification*
  • Child Development Disorders, Pervasive / diagnosis
  • Diagnostic and Statistical Manual of Mental Disorders*
  • Humans
  • Severity of Illness Index