Ovarian stimulation in cancer patients

Fertil Steril. 2013 May;99(6):1476-84. doi: 10.1016/j.fertnstert.2013.03.029.


The patients referred for fertility preservation owing to a malignant disease do not represent the typical population of subfertile patients treated in IVF units. Cancer may affect multiple tissues throughout the body and can result in a variety of complications during controlled ovarian stimulation. Determination of the controlled ovarian stimulation protocol and gonadotropin dose for oocyte/embryo cryopreservation requires an individualized assessment. This review highlights the new protocols that are emerging to reduce time constraints and emphasizes management considerations to decrease complications.

Publication types

  • Review

MeSH terms

  • Cryopreservation / methods
  • Cryopreservation / trends
  • Female
  • Fertility Preservation / methods
  • Fertility Preservation / trends*
  • Gonadotropins / administration & dosage
  • Humans
  • Neoplasms / epidemiology
  • Neoplasms / physiopathology*
  • Neoplasms / therapy*
  • Ovulation Induction / methods
  • Ovulation Induction / trends*


  • Gonadotropins