Rapid interaction between CTLA4-Ig (abatacept) and synovial macrophages from patients with rheumatoid arthritis

J Rheumatol. 2013 May;40(5):738-40. doi: 10.3899/jrheum.120866.
No abstract available

Publication types

  • Letter

MeSH terms

  • Abatacept
  • Antirheumatic Agents / pharmacology*
  • Arthritis, Rheumatoid / genetics
  • Arthritis, Rheumatoid / metabolism
  • Arthritis, Rheumatoid / pathology*
  • Biomarkers / metabolism
  • Cells, Cultured
  • Cytokines / genetics
  • Cytokines / metabolism
  • Down-Regulation / drug effects
  • Female
  • Gene Expression / drug effects
  • Humans
  • Immunoconjugates / pharmacology*
  • Macrophages / drug effects*
  • Macrophages / pathology
  • Male
  • Middle Aged
  • Synovectomy
  • Synovial Membrane / drug effects*
  • Synovial Membrane / pathology
  • Time Factors
  • Transforming Growth Factor beta / genetics
  • Transforming Growth Factor beta / metabolism

Substances

  • Antirheumatic Agents
  • Biomarkers
  • Cytokines
  • Immunoconjugates
  • Transforming Growth Factor beta
  • Abatacept