Systemic transthyretin amyloidosis in a patient with bent spine syndrome

Amyloid. 2013 Jun;20(2):131-4. doi: 10.3109/13506129.2013.792248. Epub 2013 May 2.

Abstract

Wild-type and mutant transthyretin (TTR) are implicated in systemic amyloidosis (ATTR). Myopathy is a rare complication of ATTR amyloidosis, however no patient with bent spine syndrome secondary to ATTR amyloidosis has been reported so far. We present the first case of bent spine syndrome in a patient with wild-type ATTR amyloidosis who also had concomitant Alzheimer's disease.

Publication types

  • Case Reports

MeSH terms

  • Aged
  • Alzheimer Disease / complications*
  • Alzheimer Disease / pathology
  • Amyloid Neuropathies, Familial / complications*
  • Amyloid Neuropathies, Familial / genetics
  • Amyloid Neuropathies, Familial / pathology
  • Humans
  • Male
  • Muscular Diseases / etiology*
  • Muscular Diseases / pathology
  • Prognosis
  • Spinal Curvatures / etiology*
  • Spinal Curvatures / pathology

Supplementary concepts

  • Amyloidosis, Hereditary, Transthyretin-Related