Prospective predictors of unprotected anal intercourse among HIV-seropositive men who have sex with men initiating antiretroviral therapy

AIDS Behav. 2014 Jan;18(1):78-87. doi: 10.1007/s10461-013-0477-1.


Contemporary HIV prevention efforts are increasingly focused on those already living with HIV/AIDS (i.e., "prevention with positives"). Key to these initiatives is research identifying the most risky behavioral targets. Using a longitudinal design, we examined socio-demographic and psychosocial factors that prospectively predicted unprotected anal intercourse (UAI) in a sample of 134 HIV-seropositive men who have sex with men (MSM) initiating, changing, or re-starting an antiretroviral therapy regimen as part of a behavioral intervention study. Computer-based questionnaires were given at baseline and 6 months. In a sequential logistic regression, baseline measures of UAI (step 1), socio-demographic factors such as Latino ethnicity (step 2), and psychosocial factors such as crystal methamphetamine use, greater life stress, and lower trait anxiety (step 3) were predictors of UAI at 6 months. Problem drinking was not a significant predictor. Prevention efforts among MSM living with HIV/AIDS might focus on multiple psychosocial targets, like decreasing their crystal methamphetamine use and teaching coping skills to deal with life stress.

Publication types

  • Randomized Controlled Trial
  • Research Support, N.I.H., Extramural

MeSH terms

  • Adult
  • Anti-HIV Agents / therapeutic use*
  • Drug Administration Schedule
  • HIV Infections / prevention & control
  • HIV Infections / psychology*
  • HIV Infections / transmission
  • HIV Seropositivity / diagnosis
  • HIV Seropositivity / epidemiology
  • HIV Seropositivity / psychology*
  • Health Knowledge, Attitudes, Practice
  • Homosexuality, Male* / ethnology
  • Homosexuality, Male* / statistics & numerical data
  • Humans
  • Interviews as Topic
  • Latin America / ethnology
  • Logistic Models
  • Longitudinal Studies
  • Male
  • Middle Aged
  • Prospective Studies
  • Sexual Behavior*
  • Socioeconomic Factors
  • Stress, Psychological
  • Substance-Related Disorders / epidemiology
  • Surveys and Questionnaires
  • Unsafe Sex / psychology*
  • Unsafe Sex / statistics & numerical data
  • Vulnerable Populations
  • Washington / epidemiology
  • Young Adult


  • Anti-HIV Agents