Theory development from studies with young women with breast cancer who are BRCA mutation negative

ANS Adv Nurs Sci. 2013 Apr-Jun;36(2):E41-53. doi: 10.1097/ANS.0b013e3182901ff1.


Researchers and practitioners can use inductively derived theory to direct their research and practice. This article describes the ongoing development of a theory that can assist in explaining experiences of young women with breast cancer who have genetic testing for the BRCA mutation. Seventeen BRCA-negative women with breast cancer from a larger grounded theory study were interviewed. While receiving a negative BRCA mutation test result subsequent to a breast cancer diagnosis was described as a relief, the information was also confusing. The author's published Theory of Genetic Vulnerability is expanded to incorporate the outcomes of this analysis.

Publication types

  • Research Support, N.I.H., Extramural

MeSH terms

  • Adult
  • Age Factors
  • Breast Neoplasms / diagnosis
  • Breast Neoplasms / genetics*
  • Breast Neoplasms / psychology
  • Female
  • Genes, BRCA1*
  • Genes, BRCA2*
  • Genetic Counseling
  • Genetic Predisposition to Disease / psychology*
  • Genetic Testing*
  • Humans
  • Mutation*
  • Nursing Theory*
  • Qualitative Research