Inhibition by dietary D-psicose of body fat accumulation in adult rats fed a high-sucrose diet

Biosci Biotechnol Biochem. 2013;77(5):1123-6. doi: 10.1271/bbb.130019. Epub 2013 May 7.


We investigated the anti-obesity effects of dietary D-psicose on adult rats fed a high-sucrose diet. Wistar rats (16 weeks old) that had previously been fed a high-sucrose diet (HSD) were fed HSD or a high-starch diet (HTD) with or without 5% D-psicose for 8 weeks. The food efficiency, carcass fat percentage, abdominal fat accumulation, and body weight gain were all significantly suppressed by dietary D-psicose.

MeSH terms

  • Adipose Tissue / drug effects*
  • Adipose Tissue / metabolism
  • Animals
  • Body Weight / drug effects
  • Diet / adverse effects*
  • Dietary Carbohydrates / pharmacology*
  • Eating / drug effects
  • Fructose / pharmacology*
  • Male
  • Rats
  • Rats, Wistar


  • Dietary Carbohydrates
  • psicose
  • Fructose