Direct asymmetric vinylogous aldol reaction of allyl ketones with isatins: divergent synthesis of 3-hydroxy-2-oxindole derivatives

Angew Chem Int Ed Engl. 2013 Jun 24;52(26):6666-70. doi: 10.1002/anie.201302274. Epub 2013 May 3.
No abstract available

Publication types

  • Research Support, Non-U.S. Gov't

MeSH terms

  • Aldehydes / chemistry*
  • Animals
  • Carbon / chemistry
  • Catalysis
  • Chemistry, Pharmaceutical / methods*
  • Drug Design
  • Indoles / chemical synthesis*
  • Indoles / chemistry
  • Isatin / chemistry*
  • Ketones / chemistry*
  • Models, Chemical
  • Solvents / chemistry
  • Temperature
  • Tranquilizing Agents / chemical synthesis

Substances

  • Aldehydes
  • Indoles
  • Ketones
  • Solvents
  • Tranquilizing Agents
  • 3-hydroxy-2-oxoindole
  • Carbon
  • Isatin
  • 3-hydroxybutanal