What can we learn and what do we need to know amidst the iatrogenic outbreak of Exserohilum rostratum meningitis?

Clin Infect Dis. 2013 Sep;57(6):853-9. doi: 10.1093/cid/cit283. Epub 2013 May 6.


The tragedy of the ongoing epidemic of meningitis caused by Exserohilum rostratum brings into focus the epidemiology, risk factors, pathogenesis, diagnosis, and treatment of a multitude of opportunistic mold infections of the central nervous system. Herein we provide our perspective regarding the translational research objectives of this infection that are needed to make an impact on this important healthcare crisis.

Keywords: Exserohilum rostratum; antifungals; meningoencephalitis; pathogenesis; risk factors.

Publication types

  • Research Support, N.I.H., Extramural
  • Research Support, Non-U.S. Gov't

MeSH terms

  • Antifungal Agents / therapeutic use
  • Ascomycota / isolation & purification*
  • Biomedical Research
  • Disease Outbreaks*
  • Humans
  • Iatrogenic Disease / epidemiology*
  • Meningitis, Fungal / drug therapy
  • Meningitis, Fungal / epidemiology
  • Meningitis, Fungal / microbiology*
  • Prognosis
  • Risk Factors
  • Treatment Outcome
  • Virulence Factors


  • Antifungal Agents
  • Virulence Factors