Skip to main page content
Access keys NCBI Homepage MyNCBI Homepage Main Content Main Navigation
, 14 (4), 402

Raymond Gosling: The Man Who Crystallized Genes


Raymond Gosling: The Man Who Crystallized Genes

Naomi Attar. Genome Biol.


On April 25th 1953, three publications in Nature forever changed the face of the life sciences in reporting the structure of DNA. Sixty years later, Raymond Gosling shares his memories of the race to the double helix.


Figure 1
Figure 1
Prof (Emeritus) Raymond Gosling DSc FKC. A portrait of Ray Gosling. © Raymond Gosling; reproduced with permission.
Figure 2
Figure 2
An early X-ray diffraction pattern of crystalline DNA. An example of an early X-ray diffraction pattern image of crystalline DNA taken by Ray Gosling at King's College. Later, the arrival of Rosalind Franklin spurred an improvement in the quality of these patterns. © Raymond Gosling; reproduced with permission.
Figure 3
Figure 3
Photo 51. Rosalind Franklin's Photo 51 of 'B' form DNA, which was the highest quality X-ray diffraction pattern of DNA at the time, and an important contribution to Watson and Crick's work on the double helix. © Nature Publishing Group; reproduced with permission.
Figure 4
Figure 4
'A' form DNA. An example of an X-ray diffraction pattern obtained by Rosalind Franklin and Raymond Gosling from 'A' form DNA, which is distinct from the 'B' structure predominately found in vivo. Before embarking on the determination of the 'B' form structure, Franklin and Gosling had set out to determine the structure of 'A' form DNA from first principles. © Raymond Gosling; reproduced with permission.

Similar articles

See all similar articles

Cited by 3 articles

  • The RBPome: where the brains meet the brawn.
    Attar N. Attar N. Genome Biol. 2014 Jan 31;15(1):402. doi: 10.1186/gb4153. Genome Biol. 2014. PMID: 24485298 Free PMC article. No abstract available.
  • The DNA60IFX contest.
    Schatz MC, Taylor J, Schelhorn SE. Schatz MC, et al. Genome Biol. 2013 Jun 28;14(6):124. doi: 10.1186/gb-2013-14-6-124. Genome Biol. 2013. PMID: 23809492 Free PMC article. No abstract available.
  • Sixty years of genome biology.
    Doolittle WF, Fraser P, Gerstein MB, Graveley BR, Henikoff S, Huttenhower C, Oshlack A, Ponting CP, Rinn JL, Schatz MC, Ule J, Weigel D, Weinstock GM. Doolittle WF, et al. Genome Biol. 2013 Apr 25;14(4):113. doi: 10.1186/gb-2013-14-4-113. Genome Biol. 2013. PMID: 23651518 Free PMC article.


    1. Watson JD, Crick FH. Molecular structure of nucleic acids; a structure for deoxyribose nucleic acid. Nature. 1953;171:737–738. doi: 10.1038/171737a0. - DOI - PubMed
    1. Brenda Maddox. Rosalind Franklin: the Dark Lady of DNA. London: HarperCollins; 2002.
    1. Franklin RE, Gosling RG. Molecular configuration in sodium thymonucleate. Nature. 1953;171:740–741. doi: 10.1038/171740a0. - DOI - PubMed
    1. Wilkins MHF, Stokes AR, Wilson HR. Molecular structure of deoxypentose nucleic acids. Nature. 1953;171:738–740. doi: 10.1038/171738a0. - DOI - PubMed
    1. James Watson D. The Double Helix: a Personal Account of the Discovery of the Structure of DNA. Weidenfeld & Nicolson; 1968.

Personal name as subject

LinkOut - more resources