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. 2013 Sep;23(9):2555-60.
doi: 10.1007/s00330-013-2859-1. Epub 2013 May 8.

Increase in Left Liver Lobe Function After Preoperative Right Portal Vein Embolisation Assessed With gadolinium-EOB-DTPA MRI

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Increase in Left Liver Lobe Function After Preoperative Right Portal Vein Embolisation Assessed With gadolinium-EOB-DTPA MRI

Dominik Geisel et al. Eur Radiol. .

Abstract

Objectives: To prospectively evaluate the early development of regional liver function after right portal vein embolisation (PVE) with Gd-EOB-DTPA-enhanced MRI in patients scheduled for extended right hemihepatectomy.

Methods: Ten patients who received a PVE before an extended hemihepatectomy were examined before and 14 days after PVE using Gd-EOB-DTPA-enhanced MRI of the liver. In these sequences representative region of interest measurements were performed in the embolised right (RLL) and the non-embolised left liver lobe (LLL). The volume as well as hepatic uptake index (HUI) was calculated independently for each lobe.

Results: Relative enhancement 14 days after PVE decreased in the RLL and increased significantly in the LLL (P < 0.05). Average hepatic uptake index (HUI) for RLL was significantly lower 14 days after PVE than before PVE (P < 0.05) and significantly higher for LLL (P < 0.05).

Conclusions: A significant shift of contrast uptake from the right to the left liver lobe can be depicted as early as 14 days after right PVE by using Gd-EOB-DTPA-enhanced MRI, which could reflect the redirected portal venous blood flow and the rapid utilisation of a hepatic functional reserve.

Key points: • Preoperative portal vein embolisation (PVE) is widely performed before right-sided hepatic resection. • PVE increases intravenous contrast medium uptake in the left lobe of liver. • The hepatic uptake index for the left liver lobe increases rapidly after PVE. • Left liver lobe function increase may be visualised by Gd-EOB-DTPA-enhanced MRI.

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References

    1. Eur Radiol. 2013 Jan;23(1):174-81 - PubMed
    1. Ann Surg. 2011 Apr;253(4):656-65 - PubMed
    1. J Nucl Med. 2011 Feb;52(2):294-302 - PubMed
    1. Surgery. 2002 Jan;131(1):26-33 - PubMed
    1. World J Surg. 2009 Apr;33(4):797-803 - PubMed

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