DAPPLE: a pipeline for the homology-based prediction of phosphorylation sites

Bioinformatics. 2013 Jul 1;29(13):1693-5. doi: 10.1093/bioinformatics/btt265. Epub 2013 May 8.


Summary: While many experimentally characterized phosphorylation sites exist for certain organisms, such as human, rat and mouse, few sites are known for other organisms, hampering related research efforts. We have developed a software pipeline called DAPPLE that automates the process of using known phosphorylation sites from other organisms to identify putative sites in an organism of interest.

Availability: DAPPLE is available as a web server at http://saphire.usask.ca.

Supplementary information: Supplementary data are available at Bioinformatics online.

Publication types

  • Research Support, Non-U.S. Gov't

MeSH terms

  • Animals
  • Cattle
  • Humans
  • Phosphoproteins / chemistry*
  • Phosphoproteins / metabolism*
  • Phosphorylation
  • Sequence Analysis, Protein
  • Sequence Homology, Amino Acid
  • Software*


  • Phosphoproteins