Highly-sensitive troponin I is increased in patients with gynecological cancers

Clin Biochem. 2013 Aug;46(12):1135-1138. doi: 10.1016/j.clinbiochem.2013.04.029. Epub 2013 May 6.


Objectives: To investigate troponin I (TnI) in patients with gynecological cancers.

Methods: Highly-sensitive (HS) and conventional TnI were measured in 25 patients with untreated ovarian cancer, 25 with endometriosis and 25 with benign masses.

Results: Both HS and conventional TnI were increase in cancer patients. Values above the cut-off were found in 44% and 16% cancer patients using HS and conventional TnI methods, respectively.

Conclusions: Cardiac involvement is frequent in patients with gynecological cancers and should be preferably assessed using HS troponin immunoassays.

Keywords: Cancer; Gynecological cancer; Highly-sensitive immunoassays; Troponin.

MeSH terms

  • Adult
  • Female
  • Genital Neoplasms, Female / blood*
  • Humans
  • Immunoassay / methods*
  • Middle Aged
  • Sensitivity and Specificity
  • Troponin I / blood*


  • Troponin I