Sleep-related adductor laryngeal dystonia causing sleep apnea: a sleep-related breathing disorder diagnosed with sleep endoscopy and treated with botulinum toxin

Laryngoscope. 2013 Jun;123(6):1560-3. doi: 10.1002/lary.23708. Epub 2013 May 10.

Abstract

Obstructive sleep apnea syndrome (OSAS) is a chronic condition, characterized by recurrent episodes of upper airway collapse during sleep, which affects up to 5% of adults in the Western population. The muscle tone of the human body ordinarily relaxes during sleep, thus causing airway obstruction and leading to sleep apnea. We report a case of a 68-years old male in which dystonic closure of the larynx during sleep caused OSAS. The sleep endoscopy was crucial in establishing the diagnosis of laryngeal dystonia. A botulinum toxin injection in the vocal cord improved the OSAS. These findings define a novel sleep-related breathing disorder.

Publication types

  • Case Reports

MeSH terms

  • Aged
  • Anti-Dyskinesia Agents / therapeutic use
  • Botulinum Toxins / therapeutic use*
  • Dystonia / complications
  • Dystonia / diagnosis*
  • Dystonia / drug therapy
  • Endoscopy / methods*
  • Follow-Up Studies
  • Humans
  • Laryngeal Diseases / complications
  • Laryngeal Diseases / diagnosis*
  • Laryngeal Diseases / drug therapy
  • Male
  • Polysomnography
  • Sleep Apnea Syndromes / diagnosis
  • Sleep Apnea Syndromes / drug therapy
  • Sleep Apnea Syndromes / etiology*
  • Sleep*

Substances

  • Anti-Dyskinesia Agents
  • Botulinum Toxins