Barbed versus standard suture: a randomized trial for laparoscopic vaginal cuff closure

Abstract

Study objective: To compare closure times, cuff healing, and postoperative dyspareunia between barbed and traditional sutures during laparoscopic total hysterectomy.

Design: A randomized clinical trial (Canadian Task Force classification I).

Setting: A university hospital.

Patients: Sixty-three women undergoing total laparoscopic hysterectomy.

Interventions: Total laparoscopic hysterectomy was performed using standard techniques. The vaginal cuff closure method was randomized to barbed suture (Quill; Angiotech Pharmaceuticals, Inc., Vancouver, Canada) or standard suture (Vicryl; Ethicon Inc., Somerville, NJ). The time required for cuff closure was documented. Patients were examined postoperatively to assess cuff healing, and a standardized sexual function questionnaire was administered preoperatively and at 3 months postoperatively.

Measurements and main results: The mean vaginal cuff closure time was 10.4 minutes versus 9.6 minutes in the barbed versus standard suture group (p = .51). Cuff healing appeared similar between the 2 groups. Rates of dyspareunia, partner dyspareunia, and sexual function were similar in both groups at 3 months postoperatively. Vaginal cuff closure times were significantly faster among attendings compared with residents/fellows (7.1 vs. 12.8 minutes, respectively; p < .0001). The study was designed to have a statistical power of 80% to detect a difference of 5 minutes in cuff closure time between the 2 groups (α level of 0.05).

Conclusion: Laparoscopic vaginal cuff closure times are similar when using barbed sutures and braided sutures.

Keywords: Barbed suture; Laparoscopy; Total hysterectomy; Vaginal cuff.