Outcomes of complete radical hysterectomy in early-stage cervical cancer patients with intra-operative detection of nodal metastases

J Med Assoc Thai. 2013 Mar:96 Suppl 3:S35-41.

Abstract

Objective: To determine the overall 5-year survival rate and treatment-related complications in stage IB-IIA cervical cancer patients with intra-operative detection of pelvic node metastases who underwent complete radical hysterectomy and systematic lymphadenectomy.

Material and method: The medical records of FIGO stage IB-IIA cervical cancer patients who underwent radical hysterectomy and pelvic lymphadenectomy in Rajavithi Hospital between January 1985 and December 2006 were retrospectively reviewed. Of the 247 node-positive stage IB-IIA cervical cancer patients, 121 patients displayed evidence of intra-operative detection and underwent complete radical hysterectomy with systematic lymphadenectomy. These 121 patients were reviewed of which 107 were in stage IB and 14 were in stage IIA. Overall 5-year survival rate and treatment-related complications were investigated.

Results: The median follow-up period was 117 months (range 60-312 months). Of the 121 stage IB-IIA cervical cancer

Patients: with intra-operative detection of pelvic node metastases who underwent complete radical hysterectomy and pelvic lymphadenectomy, the overall 5-year survival rate was 70.5%. The major treatment-related complications were intraoperative hemorrhage and post-operative bladder atony which accounted for 43.0% and 10.7%, respectively.

Conclusion: Early-stage cervical cancer patients with intra-operative detection of pelvic node metastases who underwent complete radical hysterectomy had favorable survival outcomes and manageable complications.

MeSH terms

  • Adult
  • Female
  • Humans
  • Hysterectomy*
  • Lymph Node Excision
  • Lymphatic Metastasis / pathology*
  • Neoplasm Staging
  • Postoperative Complications
  • Retrospective Studies
  • Survival Rate
  • Treatment Outcome
  • Uterine Cervical Neoplasms / pathology*
  • Uterine Cervical Neoplasms / surgery*