Reduction of cue-induced craving through realtime neurofeedback in nicotine users: the role of region of interest selection and multiple visits

Psychiatry Res. 2013 Jul 30;213(1):79-81. doi: 10.1016/j.pscychresns.2013.03.003. Epub 2013 May 15.


This multi-visit, real-time functional magnetic resonance imaging feedback study demonstrates that treatment-seeking smokers can effectively modulate their behavioral and brain responses to smoking cues. They are more effective at decreasing activity in functionally defined regions involved in "craving" (e.g. ventral anterior cingulate cortex (vACC)) rather than increasing activity in regions involved in "resisting" (e.g. dorsal medial prefrontal cortex (dmPFC)).

MeSH terms

  • Adult
  • Behavior, Addictive / physiopathology*
  • Behavior, Addictive / therapy*
  • Cues
  • Functional Neuroimaging
  • Gyrus Cinguli / physiopathology*
  • Humans
  • Magnetic Resonance Imaging
  • Middle Aged
  • Neurofeedback / physiology*
  • Prefrontal Cortex / physiopathology*
  • Smoking Cessation / psychology*