[Influenza infection and pregnancy]

Presse Med. 2013 Nov;42(11):1453-60. doi: 10.1016/j.lpm.2013.01.064. Epub 2013 May 15.
[Article in French]


Pregnant woman have an increased risk of respiratory complications and hospitalization related to influenza. The flu, like any systemic infection, may also be responsible for uterine contractions constituting a threat of miscarriage or premature labor according to gestational age at which it occurs. There is no specific recommendation regarding the management of influenza-like illness in pregnant women, but a nasopharyngeal sample can be performed in the presence of respiratory or general symptoms occurring during an epidemic to search influenza and establish if a specific treatment with oseltamivir (Tamiflu(®)). Surveillance in hospital or intensive care unit may be necessary. Vaccination against influenza provides a satisfactory immunity in pregnant women and reduces the risk of respiratory complications. Transplacental passage of maternal antibody protects newborns who are more likely to have severe influenza infection and because the vaccine cannot be administered before the age of 6 months. The available data show good tolerance influenza vaccination performed during pregnancy. Since 2012, vaccination against seasonal influenza is recommended for pregnant women, whatever the stage of pregnancy at the time of the vaccination campaign.

Publication types

  • English Abstract
  • Review

MeSH terms

  • Adult
  • Female
  • Humans
  • Immunity, Maternally-Acquired / immunology*
  • Influenza A Virus, H1N1 Subtype*
  • Influenza Vaccines / administration & dosage*
  • Influenza, Human / complications
  • Influenza, Human / immunology
  • Influenza, Human / prevention & control*
  • Influenza, Human / therapy
  • Pregnancy
  • Pregnancy Complications, Infectious / immunology
  • Pregnancy Complications, Infectious / prevention & control*
  • Pregnancy Complications, Infectious / therapy
  • Pregnancy Outcome
  • Vaccination*


  • Influenza Vaccines