A case of Churg-Strauss syndrome and central retinal artery occlusion with good visual recovery

Indian J Ophthalmol. 2013 Apr;61(4):178-9. doi: 10.4103/0301-4738.112164.

Abstract

Here we report a case of Churg-Strauss syndrome (CSS) and central retinal artery occlusion (CRAO), with good visual recovery. A 58-year-old Japanese man with CSS experienced acute painless loss of vision in his right eye. CRAO was diagnosed by fundoscopic findings (retinal whitening with a cherry-red spot). Steroid pulse therapy (methylprednisolone at 1 g daily for 3 days) followed by combined treatment with prednisolone (30 mg/day) and cyclophosphamide (150 mg/day) was administered; his visual acuity recovered to 20/30 in 1 month, and no recurrence has occurred for 1 year. Steroid pulse therapy may be effective for CRAO in CSS patients.

Publication types

  • Case Reports

MeSH terms

  • Churg-Strauss Syndrome / complications*
  • Cyclophosphamide / administration & dosage*
  • Glucocorticoids / administration & dosage
  • Humans
  • Immunosuppressive Agents / administration & dosage
  • Male
  • Middle Aged
  • Prednisolone / administration & dosage*
  • Pulse Therapy, Drug
  • Recovery of Function / drug effects*
  • Retinal Artery Occlusion* / drug therapy
  • Retinal Artery Occlusion* / etiology
  • Retinal Artery Occlusion* / pathology

Substances

  • Glucocorticoids
  • Immunosuppressive Agents
  • Cyclophosphamide
  • Prednisolone