Deletions in chromosome 2 and fragile sites

Am J Med Genet. 1990 Jun;36(2):214-8. doi: 10.1002/ajmg.1320360215.

Abstract

We report on 2 patients with de novo deletions of 2q and chromosome constitutions of 46,XY,del(2)(q32.3q33.3) and 46,XX,del(2) (q21q23.2), respectively. Comparisons of breakpoints of interstitial deletions show frequent correspondence to common fragile sites.

Publication types

  • Case Reports
  • Comparative Study

MeSH terms

  • Cells, Cultured
  • Chromosome Aberrations*
  • Chromosome Banding
  • Chromosome Deletion*
  • Chromosome Fragile Sites
  • Chromosome Fragility*
  • Chromosomes, Human, Pair 2
  • Female
  • Humans
  • Infant
  • Infant, Newborn
  • Male