Hypertension, obesity, and coronary artery disease in the survivors of congenital heart disease

Can J Cardiol. 2013 Jul;29(7):841-8. doi: 10.1016/j.cjca.2013.03.021. Epub 2013 May 18.


Obesity, hypertension, and coronary artery disease are prevalent in the general population and well recognized as contributors to cardiac morbidity and mortality. With surgical and medical advances, there is a growing and aging population with congenital heart disease who are also at risk of developing these comorbidities. In addition, some congenital cardiac lesions predispose patients to conditions such as hypertension or coronary artery disease. The effect of these comorbidities on the structurally abnormal heart is not well understood, but might be very important, especially in those with residual abnormalities. Thus, in addition to surveillance for and treatment of late complications it is important for the congenital cardiologist to consider and aggressively manage acquired comorbidities. In this review we explore the prevalence of hypertension, obesity, and coronary artery disease, discuss congenital lesions that predispose to these conditions and review management strategies for this unique population.

Publication types

  • Research Support, Non-U.S. Gov't
  • Review

MeSH terms

  • Coronary Artery Disease / epidemiology
  • Coronary Artery Disease / physiopathology*
  • Coronary Artery Disease / therapy
  • Heart Defects, Congenital / epidemiology
  • Heart Defects, Congenital / physiopathology*
  • Heart Defects, Congenital / therapy
  • Humans
  • Hypertension / epidemiology
  • Hypertension / physiopathology*
  • Hypertension / therapy
  • Obesity / epidemiology
  • Obesity / physiopathology*
  • Obesity / therapy
  • Prevalence
  • Risk Factors
  • Survivors