Gastrointestinal bleeding and aortic stenosis (Heyde syndrome): the role of aortic valve replacement

J Card Surg. 2013 Jul;28(4):414-6. doi: 10.1111/jocs.12131. Epub 2013 May 20.


Heyde syndrome (the combination of iron deficiency anemia and aortic stenosis) has been a controversial entity. The proposed mechanisms between aortic valve disease and iron deficiency anemia are examined in this article along with impact valve replacement on iron deficiency anemia.

Publication types

  • Case Reports
  • Review

MeSH terms

  • Aged
  • Anemia, Iron-Deficiency / etiology
  • Anemia, Iron-Deficiency / surgery*
  • Aortic Valve / surgery*
  • Aortic Valve Stenosis / etiology
  • Aortic Valve Stenosis / surgery*
  • Bioprosthesis
  • Female
  • Gastrointestinal Hemorrhage / etiology*
  • Heart Valve Prosthesis Implantation*
  • Humans
  • Syndrome
  • von Willebrand Diseases / etiology