Geotrichum capitatum septicemia in a hematological malignancy patient with positive galactomannan antigen: case report and review of the literature

Turk J Pediatr. 2012 Nov-Dec;54(6):674-8.

Abstract

Geotrichum capitatum, formerly known as Trichosporon capitatum, is an uncommon but frequently fatal invasive fungal infection in immunocompromised patients, especially in hematological malignancies. We report a seven-year-old patient with acute myeloid leukemia with Geotrichum septicemia with involvement of the lungs, liver, spleen, and kidneys, who had a favorable outcome after therapy. Alteration of antifungal treatment to liposomal amphotericin B resolved the fever with favorable clinical response.

Publication types

  • Case Reports
  • Review

MeSH terms

  • Child
  • Galactose / analogs & derivatives
  • Geotrichosis / complications
  • Geotrichosis / immunology
  • Geotrichosis / microbiology*
  • Geotrichum / isolation & purification*
  • Humans
  • Immunocompromised Host*
  • Leukemia, Myeloid, Acute / complications
  • Leukemia, Myeloid, Acute / immunology*
  • Male
  • Mannans / immunology*
  • Sepsis / complications
  • Sepsis / immunology
  • Sepsis / microbiology*

Substances

  • Mannans
  • galactomannan
  • Galactose