Skip to main page content
Access keys NCBI Homepage MyNCBI Homepage Main Content Main Navigation
, 6 (1), 16

Non-traumatic Splenic Rupture in a Patient on Oral Anticoagulation

Affiliations

Non-traumatic Splenic Rupture in a Patient on Oral Anticoagulation

Marije M de Kubber et al. Int J Emerg Med.

Abstract

Background: Splenic injury is normally associated with trauma, but spontaneous splenic rupture has been described in various systemic diseases.

Case presentation: A 56-year-old male on oral anticoagulation presented to the emergency department with epigastric pain, nausea, and left upper quadrant tenderness. There was no history of trauma. Contrast-enhanced CT imaging revealed a large subcapsular haematoma of the spleen. Oral anticoagulation was antagonised with vitamin K and the patient was discharged in good condition after 3 days of clinical observation.

Conclusion: Non-traumatic splenic rupture is a rare complication of oral anticoagulation.

Figures

Figure 1
Figure 1
Contrast-enhanced computed tomography image with 5-mm slides in transverse (A) and coronal (B) orientation. Spleen (S) with large subcapsular hematoma (H) with an estimated volume of 0.75 l.

Similar articles

See all similar articles

Cited by 6 PubMed Central articles

See all "Cited by" articles

References

    1. Blankenship JC, Indeck M. Spontaneous splenic rupture complicating anticoagulant or thrombolytic therapy. Am J Med. 1993;6(4):433–437. doi: 10.1016/0002-9343(93)90156-J. - DOI - PubMed
    1. Stassen NA, Bhullar I, Cheng JD, Crandall ML, Friese RS, Guillamondegui OD, Jawa RS, Maung AA, Rohs TJ Jr, Sangosanya A, Schuster KM, Seamon MJ, Tchorz KM, Zarzuar BL, Kerwin AJ. Eastern Association for the Surgery of Trauma. Selective nonoperative management of blunt splenic injury: an Eastern Association for the Surgery of Trauma practice management guideline. J Trauma Acute Care Surg. 2012;6((5 Suppl 4)):S294–300. Nov; - PubMed
    1. Renzulli P, Hostettler A, Schoepfer AM, Gloor B, Candinas D. Systematic review of atraumatic splenic rupture. Br J Surg. 2009;6(10):1114–1121. doi: 10.1002/bjs.6737. - DOI - PubMed
    1. Jeffrey RB, Laing FC, Federle MP, Goodman PC. Computed tomography of splenic trauma Radiology. Radiology. 1981;6(3):729–732. - PubMed

LinkOut - more resources

Feedback