Haemangioma: clinical course, complications and management

Br J Dermatol. 2013 Jul;169(1):20-30. doi: 10.1111/bjd.12436.


Despite their high incidence, most infantile haemangiomas (IH) do not require treatment as they regress spontaneously and most do not leave significant sequelae. For the subset of haemangiomas that require treatment, indications for intervention can be divided into three main categories: ulceration, disfigurement and impairment of function or vital structures. In addition, certain IH have a risk of associated structural anomalies. Given the wide heterogeneity of haemangiomas, deciding which haemangiomas need intervention and when to intervene requires a detailed knowledge of natural history and clinical indicators of increased risk.

Publication types

  • Review

MeSH terms

  • Administration, Cutaneous
  • Adrenal Cortex Hormones / therapeutic use
  • Adrenergic beta-Antagonists / therapeutic use
  • Cicatrix / etiology
  • Congenital Abnormalities / etiology
  • Dermatologic Agents / therapeutic use
  • Hemangioma / complications*
  • Hemangioma / drug therapy
  • Hemangioma / pathology
  • Humans
  • Propranolol / therapeutic use
  • Skin Neoplasms / complications*
  • Skin Neoplasms / drug therapy
  • Skin Neoplasms / pathology
  • Skin Ulcer / drug therapy
  • Skin Ulcer / etiology


  • Adrenal Cortex Hormones
  • Adrenergic beta-Antagonists
  • Dermatologic Agents
  • Propranolol