A genetic deletion of the serotonin transporter greatly enhances the reinforcing properties of MDMA in rats

Mol Psychiatry. 2014 May;19(5):534-5. doi: 10.1038/mp.2013.75. Epub 2013 May 28.
No abstract available

Publication types

  • Letter
  • Research Support, Non-U.S. Gov't

MeSH terms

  • Amphetamine-Related Disorders / genetics
  • Amphetamine-Related Disorders / physiopathology*
  • Animals
  • Dose-Response Relationship, Drug
  • Gene Deletion
  • Gene Knockout Techniques
  • Kaplan-Meier Estimate
  • N-Methyl-3,4-methylenedioxyamphetamine / pharmacology*
  • RNA-Binding Proteins / genetics
  • RNA-Binding Proteins / metabolism*
  • Rats, Transgenic
  • Reinforcement, Psychology*
  • Self Administration
  • Serotonin Agents / pharmacology*

Substances

  • RNA-Binding Proteins
  • Serotonin Agents
  • Sert1 protein, rat
  • N-Methyl-3,4-methylenedioxyamphetamine