Regioselective diazo-transfer reaction at the C3-position of the 2-desoxystreptamine ring of neamine antibiotics

Chemistry. 2013 Jul 8;19(28):9151-4. doi: 10.1002/chem.201300912. Epub 2013 May 27.

Authors

Andreas A Bastian¹, Eliza M Warszawik, Praveen Panduru, Christoph Arenz, Andreas Herrmann

Affiliation

¹ Department of Polymer Chemistry, Zernike Institute for Advanced Materials, University of Groningen, Nijenborgh 4, 9747 AG Groningen, The Netherlands.

PMID: 23712621
DOI: 10.1002/chem.201300912

No abstract available

Keywords: antibiotics; diazo-transfer; drug design; modification; regioselectivity.

Publication types

Research Support, Non-U.S. Gov't

MeSH terms

Anti-Bacterial Agents / chemical synthesis*
Anti-Bacterial Agents / chemistry
Azides / chemistry
Framycetin / chemical synthesis*
Framycetin / chemistry
Imidazoles / chemistry
Stereoisomerism

Substances

Anti-Bacterial Agents
Azides
Imidazoles
imidazole-1-sulfonyl azide hydrochloride
Framycetin
neamine