Impact of multidrug-resistant organisms on patients considered for lung transplantation

Infect Dis Clin North Am. 2013 Jun;27(2):343-58. doi: 10.1016/j.idc.2013.02.006. Epub 2013 Apr 17.


Infections with multidrug-resistant organisms are a growing problem in lung transplant recipients. Carriage of drug-resistant bacteria and fungi before transplantation is an important risk factor for such infections. In that regard Pseudomonas aeruginosa and species of Burkholderia, Acinetobacter, non-tuberculous mycobacteria and Scedosporium are particularly important. An understanding of the impact of these organisms is essential to the evaluation of lung transplant candidates. The microbiology, epidemiology, clinical manifestations, and approach to these pathogens before transplant are reviewed in this article.

Publication types

  • Review

MeSH terms

  • Anti-Bacterial Agents / therapeutic use*
  • Bacteria / classification
  • Bacteria / isolation & purification
  • Bacterial Infections / drug therapy*
  • Bacterial Infections / prevention & control
  • Drug Resistance, Multiple, Bacterial*
  • Humans
  • Immunocompromised Host*
  • Lung Transplantation*
  • Opportunistic Infections / drug therapy*
  • Opportunistic Infections / prevention & control
  • Precision Medicine / methods
  • Transplantation*


  • Anti-Bacterial Agents