Serum drug level-related sodium valproate-induced hair loss

Indian J Pharmacol. 2013 Mar-Apr;45(2):187-8. doi: 10.4103/0253-7613.108315.

Abstract

Sodium valproate is a well-established treatment in epilepsy and mood disorders. Its utility is compromised by its adverse effects such as tremor, weight gain, hair loss, and liver dysfunction. Hair loss may occur when drug is used in higher dose. Drug-induced hair loss is diffused and non-scarring, which is reversible upon withdrawal. But there are no case reports showing relation between serum levels of valproate and occurrence of hair loss. So we took interest in reporting this case report.

Keywords: Drug-induced hair loss; serum drug level; valproate.

Publication types

  • Case Reports

MeSH terms

  • Adult
  • Alopecia / blood
  • Alopecia / chemically induced*
  • Anticonvulsants / administration & dosage
  • Anticonvulsants / adverse effects*
  • Dose-Response Relationship, Drug
  • Female
  • Hair / drug effects*
  • Humans
  • Seizures / drug therapy*
  • Valproic Acid / administration & dosage
  • Valproic Acid / adverse effects*

Substances

  • Anticonvulsants
  • Valproic Acid