Crohn's disease presenting as a neutrophilic dermatosis in a 5-month-old boy

Pediatr Dermatol. 2013 Sep-Oct;30(5):619-20. doi: 10.1111/pde.12156. Epub 2013 May 31.

Abstract

A 5-month-old boy with a previous history of failure to thrive and poor feeding was admitted to the hospital with failure to thrive, oral ulcers, and a generalized vesiculopustular rash that demonstrated a subcorneal pustule and neutrophilic infiltrate on histology. Esophagogastroduodenoscopy and flexible sigmoidoscopy biopsies demonstrated chronic active colitis with granulomas, consistent with the diagnosis of Crohn's disease. Our case represents, to our knowledge, the youngest person reported with this condition in association with Crohn's disease.

Publication types

  • Case Reports

MeSH terms

  • Crohn Disease / complications
  • Crohn Disease / immunology
  • Crohn Disease / pathology*
  • Failure to Thrive / etiology
  • Failure to Thrive / immunology
  • Failure to Thrive / pathology*
  • Humans
  • Infant
  • Leukocyte Disorders / congenital*
  • Leukocyte Disorders / etiology
  • Leukocyte Disorders / immunology
  • Leukocyte Disorders / pathology
  • Male
  • Skin Diseases, Vesiculobullous / etiology
  • Skin Diseases, Vesiculobullous / immunology
  • Skin Diseases, Vesiculobullous / pathology*

Supplementary concepts

  • Neutrophilia, Hereditary
  • Pediatric Crohn's disease