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. 2012 Jul;33(3):356-64.
doi: 10.4103/0974-8520.108822.

Clinical Study of Tribulus Terrestris Linn. In Oligozoospermia: A Double Blind Study

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Free PMC article

Clinical Study of Tribulus Terrestris Linn. In Oligozoospermia: A Double Blind Study

Thirunavukkarasu M Sellandi et al. Ayu. .
Free PMC article

Abstract

Infertility is a problem of global proportions, affecting on an average 8-12% of couples worldwide. Low sperm count (Oligozoospermia) is one of the main causes of male infertility and it is correlated with Kshina Shukra. The fruits of Gokshura (Tribulus terrestris. Linn) are considered to act as a diuretic and aphrodisiac; they used for urolithiasis, sexual dysfunctions, and infertility. Hence, it was planned to study the effect of Gokshura in the management of Kshina Shukra (Oligozoospermia), and to evade the preconception, a double-blind, randomized, placebo-controlled study was designed. In this study, eligible subjects between the age of 21 and 50 years, with a complaint of Kshina Shukra (Oligozoospermia), were randomized to receive either Gokshura granules or placebo granules for 60 days. The primary outcome measures were percentage changes in the Pratyatmaka Lakshanas (cardinal symptoms) of Kshina Shukra, Agni bala, Deha bala, Satva bala, the semenogram, and in the Quality of the Sexual Health Questionnaire. The placebo granules showed 70.95% improvement, whereas, the Gokshura granules showed 78.11% improvement in Rogi bala (Agni bala, Deha bala, Satva bala, and the Quality of Sexual Health) and Rogabala (Semen Analysis and Pratyatmaka Lakshanas). The Gokshura granules have shown superior results in the management of Kshina Shukra, as compared to the placebo granules.

Keywords: Gokshura; Kshina Shukra; Oligozoospermia; Tribulus terrestris.

Figures

Figure 1
Figure 1
Effect of therapy on hormone
Figure 2
Figure 2
Effect of therapy on seminal parameters
Figure 3
Figure 3
Effect of therapy on quality of sexual life
Figure 4
Figure 4
Overall effect of therapy

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