Acute kidney injury: an increasing global concern

Lancet. 2013 Jul 13;382(9887):170-9. doi: 10.1016/S0140-6736(13)60647-9. Epub 2013 May 31.


Despite an increasing incidence of acute kidney injury in both high-income and low-income countries and growing insight into the causes and mechanisms of disease, few preventive and therapeutic options exist. Even small acute changes in kidney function can result in short-term and long-term complications, including chronic kidney disease, end-stage renal disease, and death. Presence of more than one comorbidity results in high severity of illness scores in all medical settings. Development or progression of chronic kidney disease after one or more episode of acute kidney injury could have striking socioeconomic and public health outcomes for all countries. Concerted international action encompassing many medical disciplines is needed to aid early recognition and management of acute kidney injury.

Publication types

  • Review

MeSH terms

  • Acute Kidney Injury* / diagnosis
  • Acute Kidney Injury* / etiology
  • Acute Kidney Injury* / therapy
  • Cost of Illness
  • Costs and Cost Analysis
  • Developed Countries / statistics & numerical data
  • Developing Countries / statistics & numerical data
  • Global Health
  • Humans
  • Incidence
  • Income
  • Prevalence
  • Prognosis
  • Renal Replacement Therapy / methods
  • Risk Factors
  • Terminology as Topic
  • Tropical Climate