Ability of a novel blue laser imaging system for the diagnosis of colorectal polyps

Dig Endosc. 2014 Mar;26(2):250-8. doi: 10.1111/den.12127. Epub 2013 Jun 3.


Background: A new endoscope system with a laser light source, blue laser imaging (BLI), has been developed by Fujifilm that allows for narrow-band light observation. The aim of the present study was to evaluate the utility of BLI for the diagnosis of colorectal polyps.

Methods: We retrospectively analyzed 314 colorectal polyps that were examined with BLI observation at Kyoto Prefectural University of Medicine between September 2011 and January 2013. The surface and vascular patterns of polyps detected by published narrow-band imaging magnification: Hiroshima classification were used. Correlations were determined between the classifications and the histopathological diagnoses. Additionally, the ability of BLI without magnification to differentiate between neoplastic or non-neoplastic polyps was analyzed.

Results: A total of 41 hyperplastic polyps, 168 adenomas, 80 intramucosal cancer, 11 shallowly invaded submucosal cancer, and 14 deeply invaded submucosal cancer were analyzed.Hyperplastic polyp was observed in 100% of Type A lesions (39 lesions), adenoma was observed in 89.3% of Type B lesions (159 lesions), intramucosal cancer and shallowly invaded submucosal cancer was observed in 69.6% of Type C1 (92 lesions) and in 84.6% of Type C2 (13 lesions), and deeply invaded submucosal cancer was observed in 81.8% of Type C3 lesions (11 lesions). The overall diagnostic accuracy of BLI with magnification was 84.3%. Additionally, the diagnostic accuracy of BLI without magnification for differentiating between neoplastic and non-neoplastic polyps <10 mm in diameter was 95.2%, which was greater than that of white light (83.2%).

Conclusion: BLI was useful for the diagnosis of colorectal polyps.

Keywords: blue laser imaging (BLI); colorectal polyp; image-enhanced endoscopy; laser; narrow-band observation.

Publication types

  • Clinical Trial

MeSH terms

  • Adult
  • Aged
  • Aged, 80 and over
  • Biopsy
  • Colonic Polyps / diagnosis*
  • Colonic Polyps / surgery
  • Colonoscopy / methods*
  • Diagnosis, Differential
  • Equipment Design
  • Female
  • Follow-Up Studies
  • Humans
  • Lasers*
  • Male
  • Middle Aged
  • Narrow Band Imaging / instrumentation*
  • Prognosis
  • Rectum / pathology*
  • Rectum / surgery
  • Reproducibility of Results
  • Young Adult