Obesity and cancer--the update 2013

Best Pract Res Clin Endocrinol Metab. 2013 Apr;27(2):219-27. doi: 10.1016/j.beem.2013.04.005. Epub 2013 May 15.


Progress of the last five years regarding "Obesity and Cancer" with preference to cohort studies was reviewed for cancer of the colorectum, breast, endometrium, renal cell, and adenocarcinomas of the esophagus and compared to the knowledge reviewed in the year 2008. The new studies are mostly confirming what has been known also 5 years ago. Gender seems to play a role in colorectal cancer in that risk due to body fatness is much lower in women than in men. Body fatness at young adulthood is particularly related to risk of renal cancer whereas attained body fatness at a later stage of adulthood is driving the risk for postmenopausal breast and endometrial cancer. Fat distribution is playing a strong role for risk of adenocarcinoma of the esophagus and to a lesser extent also for colon cancer. Prediagnostic body fatness plays also a role in cancer recurrence and survival.

Publication types

  • Review

MeSH terms

  • Adipose Tissue / pathology
  • Body Weights and Measures / methods
  • Breast Neoplasms / epidemiology
  • Carcinoma, Renal Cell / epidemiology
  • Colorectal Neoplasms / epidemiology
  • Endometrial Neoplasms / epidemiology
  • Female
  • Humans
  • Kidney Neoplasms / epidemiology
  • Male
  • Neoplasms / epidemiology*
  • Obesity / diagnosis
  • Obesity / epidemiology*
  • Sex Factors