Peripheral ossifying fibroma: a clincal report

Compend Contin Educ Dent. 2011 Jun;32(5):E86-90.


Peripheral ossifying fibroma (POF) is a common solitary gingival overgrowth thought to arise from the gingival corium, periosteum, and periodontal ligament. Commonly used synonyms for POF include calcifying fibroblastic granuloma, peripheral fibroma with calcification, peripheral cementifying fibroma, and calcifying or ossifying fibrous epulis. Because it is possible to misdiagnose POF as pyogenic granuloma, peripheral giant cell granuloma, or odontogenic tumors, histopathological examination is, therefore, essential for accurate diagnosis, and differential diagnosis is important because of POF's tendency to recur. This article presents a case of peripheral ossifying fibroma in a 15-year-old female along with the clinical, histopathologic, and radiographic features and treatment details.

MeSH terms

  • Adolescent
  • Diagnosis, Differential
  • Female
  • Fibroma / diagnosis
  • Fibroma, Ossifying / diagnosis*
  • Gingival Diseases / diagnosis
  • Gingival Neoplasms / diagnosis*
  • Granuloma, Giant Cell / diagnosis
  • Granuloma, Pyogenic / diagnosis
  • Humans
  • Incisor / pathology
  • Maxilla / pathology
  • Odontogenic Tumors / diagnosis