Procalcitonin as a Diagnostic and Prognostic Marker for Sepsis Caused by Intestinal Infection: A Case Report

Eur Rev Med Pharmacol Sci. 2013 May;17(10):1311-3.

Abstract

Background: In recent years, procalcitonin has emerged as a promising marker for bacterial infection, with the high sensitivity and specificity.

Case presentation: This report presents a 76-year-old woman with fever, vomiting and diarrhea. The clinical and laboratory examination revealed that the patient had a suspected serious intestinal infection and sepsis. The extremely high level of procalcitonin and positive blood culture result confirmed our diagnosis.

Conclusions: Early identification of severe sepsis sometimes is very difficult. Procalcitonin is a useful tool in the early diagnosis of sepsis, differentiating from other inflammatory syndrome. The high PCT level (10 ng/ml) in this case could suggest serious bacterial infection and sepsis, and also predicts mortality and worse outcome.

Publication types

  • Case Reports

MeSH terms

  • Aged
  • Bacterial Infections / blood
  • Bacterial Infections / diagnosis*
  • Biomarkers / blood
  • C-Reactive Protein / analysis
  • Calcitonin / blood*
  • Calcitonin Gene-Related Peptide
  • Female
  • Humans
  • Intestinal Diseases / blood
  • Intestinal Diseases / diagnosis*
  • Prognosis
  • Protein Precursors / blood*
  • Sepsis / blood
  • Sepsis / diagnosis*
  • Systemic Inflammatory Response Syndrome / blood
  • Systemic Inflammatory Response Syndrome / diagnosis*

Substances

  • Biomarkers
  • CALCA protein, human
  • Protein Precursors
  • Calcitonin
  • C-Reactive Protein
  • Calcitonin Gene-Related Peptide