An infant fatality due to hydroxychloroquine poisoning

J Anal Toxicol. 1990 May-Jun;14(3):186-8. doi: 10.1093/jat/14.3.186.

Abstract

A 2 1/2-year-old boy was hospitalized following ingestion of an estimated 60 tablets of 200-mg hydroxychloroquine. Upon death from cardiorespiratory arrest, analytes from the stomach, small intestine, liver, and plasma were examined using UV spectroscopy, thin-layer chromatography, and gas chromatography/mass spectrometry. Results indicate modest drug amounts in the stomach and small intestine, but much higher levels in the blood and liver extracts, suggesting that a considerable overdose was consumed.

Publication types

  • Case Reports

MeSH terms

  • Child, Preschool
  • Chromatography, Thin Layer
  • Death
  • Gas Chromatography-Mass Spectrometry
  • Humans
  • Hydroxychloroquine / poisoning*
  • Liver / analysis
  • Male
  • Spectrophotometry, Ultraviolet

Substances

  • Hydroxychloroquine