Cardiotonic modulation in heart failure: insights from traditional Chinese medicine
- PMID: 23747774
- PMCID: PMC4024708
- DOI: 10.1016/j.jacc.2013.05.028
Cardiotonic modulation in heart failure: insights from traditional Chinese medicine
Abstract
Medicinal herbs have been used over the past centuries for restoring the body's homeostatic balance. Contemporary use of herbal supplements remains widespread in many cultures as treatment for specific ailments. Many possess cardiovascular actions, and some interact with cardiac medications. However, there is variable scientific evidence with respect to their safety and efficacy, and few have been subjected to the same rigorous evaluation processes and regulations as contemporary pharmaceuticals (1). In the field of heart failure, we have also witnessed the failure of promising naturopathic therapies like hawthorn extract in translating their potential benefits in rigorous clinical trials (2,3).
Keywords: chronic heart failure; controlled clinical trial; qili qiangxin capsules.
Comment on
-
A multicenter, randomized, double-blind, parallel-group, placebo-controlled study of the effects of qili qiangxin capsules in patients with chronic heart failure.J Am Coll Cardiol. 2013 Sep 17;62(12):1065-1072. doi: 10.1016/j.jacc.2013.05.035. Epub 2013 Jun 7. J Am Coll Cardiol. 2013. PMID: 23747768 Clinical Trial.
Similar articles
-
A multicenter, randomized, double-blind, parallel-group, placebo-controlled study of the effects of qili qiangxin capsules in patients with chronic heart failure.J Am Coll Cardiol. 2013 Sep 17;62(12):1065-1072. doi: 10.1016/j.jacc.2013.05.035. Epub 2013 Jun 7. J Am Coll Cardiol. 2013. PMID: 23747768 Clinical Trial.
-
Clinical effects of a standardized Chinese herbal remedy, Qili Qiangxin, as an adjuvant treatment in heart failure: systematic review and meta-analysis.BMC Complement Altern Med. 2016 Jul 11;16:201. doi: 10.1186/s12906-016-1174-1. BMC Complement Altern Med. 2016. PMID: 27402016 Free PMC article. Review.
-
[Comparative analysis of clinical effects according to syndrome differentiation of Qili Qiangxin Capsules on ischemic heart failure: Meta-analysis].Zhongguo Zhong Yao Za Zhi. 2019 Nov;44(22):4975-4984. doi: 10.19540/j.cnki.cjcmm.20190909.501. Zhongguo Zhong Yao Za Zhi. 2019. PMID: 31872608 Chinese.
-
[Network Meta-analysis of six Chinese patent medicines for replenishing Qi and activating blood in treatment of chronic heart failure].Zhongguo Zhong Yao Za Zhi. 2022 Aug;47(15):4221-4237. doi: 10.19540/j.cnki.cjcmm.20220510.502. Zhongguo Zhong Yao Za Zhi. 2022. PMID: 36046913 Chinese.
-
WITHDRAWN: Shengmai (a traditional Chinese herbal medicine) for heart failure.Cochrane Database Syst Rev. 2016 Apr 29;4(4):CD005052. doi: 10.1002/14651858.CD005052.pub6. Cochrane Database Syst Rev. 2016. PMID: 27128629 Free PMC article. Review.
Cited by
-
Qili Qiangxin (QLQX) capsule as a multi-functional traditional Chinese medicine in treating chronic heart failure (CHF): A review of ingredients, molecular, cellular, and pharmacological mechanisms.Heliyon. 2023 Nov 8;9(11):e21950. doi: 10.1016/j.heliyon.2023.e21950. eCollection 2023 Nov. Heliyon. 2023. PMID: 38034785 Free PMC article. Review.
-
Protective Effect of Qiliqiangxin against Doxorubicin-Induced Cardiomyopathy by Suppressing Excessive Autophagy and Apoptosis.Cardiovasc Ther. 2022 Jan 27;2022:9926635. doi: 10.1155/2022/9926635. eCollection 2022. Cardiovasc Ther. 2022. PMID: 35169398 Free PMC article.
-
Shenlijia Attenuates Doxorubicin-Induced Chronic Heart Failure by Inhibiting Cardiac Fibrosis.Evid Based Complement Alternat Med. 2021 Jul 16;2021:6659676. doi: 10.1155/2021/6659676. eCollection 2021. Evid Based Complement Alternat Med. 2021. PMID: 34326887 Free PMC article.
-
Efficacy and safety of electroacupuncture in acute decompensated heart failure: a study protocol for a randomized, patient- and assessor-blinded, sham controlled trial.BMC Complement Altern Med. 2017 Jul 11;17(1):361. doi: 10.1186/s12906-017-1864-3. BMC Complement Altern Med. 2017. PMID: 28697773 Free PMC article. Clinical Trial.
-
Therapeutic efficacy of shenmai injection as an adjuvant treatment in dilated cardiomyopathy: A protocol for systematic review.Medicine (Baltimore). 2020 Feb;99(8):e19158. doi: 10.1097/MD.0000000000019158. Medicine (Baltimore). 2020. PMID: 32080094 Free PMC article.
References
-
- Pittler MH, Guo R, Ernst E. Hawthorn extract for treating chronic heart failure. Cochrane Database Syst Rev. 2008;(1):CD005312. - PubMed
-
- Liang D, Zhang M. The thinking on TCM differential treatment of congestive heart failure. J Tradit Chin Med. 2000;20:44–7. - PubMed
-
- Li X, Zhang J, Huang J, et al. A multicenter, randomized, double-blind, parallel-group, placebo-controlled study of the effects of qili qiangxin capsules in patients with chronic heart failure. J Am Coll Cardiol. 2013;62:1065–72. - PubMed
Publication types
MeSH terms
Substances
Grants and funding
LinkOut - more resources
Full Text Sources
Other Literature Sources
Medical
Miscellaneous
