Exercise frequency, health risk factors, and diseases of the elderly

Arch Phys Med Rehabil. 2013 Nov;94(11):2046-53. doi: 10.1016/j.apmr.2013.05.013. Epub 2013 Jun 6.

Abstract

Objective: To determine the effect of exercise frequency on various diseases and risk factors of the elderly.

Design: Retrospective analysis of a randomized controlled 18-month exercise trial.

Setting: University ambulatory group setting.

Participants: Community-dwelling women aged ≥65 years (N=162) in the area of Northern Bavaria.

Intervention: Mixed, intense aerobic, resistance, and balance protocol for 18 months. Subjects were retrospectively subdivided into 2 groups according to their effective attendance over 18 months (>1-<2 vs ≥2-4 sessions/wk).

Main outcome measures: Bone mineral density (BMD), lean body mass, appendicular skeletal muscle mass by dual-energy x-ray absorptiometry, Framingham study-based 10-year coronary heart disease (CHD) risk, and number of falls by calendar method.

Results: Significant differences between the low-frequency exercise group (LF-EG) and the high-frequency exercise group (HF-EG) were observed for lumbar spine BMD (HF-EG, 2.4%±2.8% vs LF-EG, 0.3%±2.2%; P<.001) and proximal femur BMD (HF-EG, 2.4%±2.8% vs LF-EG, -0.5%±1.6%; P=.014), lean body mass (1.6%±3.4% vs 0.3%±2.6%, P=.053), and appendicular skeletal muscle mass (0.9%±4.5% vs -1.3%±3.2%, P=.011). No differences between both exercise groups were observed for 10-year CHD risk (-1.94%±4.14% vs -2.00%±3.13%; P=.943) and number of falls (0.95±1.36 vs 1.03±1.21 falls/person). Comparing the LF-EG with the less active control group (n=47), only nonsignificant effects for fall number (P=.065) and 10-year CHD risk (P=.178) were evaluated.

Conclusions: Although this result might not be generalizable across all exercise types and cohorts, it indicates that an overall exercise frequency of at least 2 sessions/wk may be crucial for impacting bone and muscle mass of elderly subjects.

Keywords: ASMM; BMD; Bone; CHD; Coronary disease; DXA; EG; Exercise; Fall, accidental; HF-EG; LBM; LF-EG; LS; Muscle; SEFIP; Senior Fitness and Prevention (study); WCG; appendicular skeletal muscle mass; bone mineral density; coronary heart disease; dual-energy x-ray absorptiometry; exercise group; high-frequency exercise group; lean body mass; low-frequency exercise group; lumbar spine; tHip; total Hip; wellness control group.

Publication types

  • Randomized Controlled Trial

MeSH terms

  • Accidental Falls / prevention & control
  • Accidental Falls / statistics & numerical data
  • Aged
  • Bone Density
  • Bone Diseases, Metabolic / epidemiology
  • Cardiovascular Diseases / epidemiology
  • Exercise / physiology*
  • Female
  • Geriatric Assessment
  • Health Behavior*
  • Health Status*
  • Humans
  • Male
  • Retrospective Studies
  • Risk Factors
  • Sarcopenia / epidemiology
  • Time Factors