[Pleura solitary fibrous tumor associated with Doege-Potter Syndrome]

Abstract

The Doege-Potter Syndrome is known as a combination of intrathoracic tumor associated to symptomatic hypoglycemia. Solitary Fibrous Tumor is a mesenchymal neoplasm. Initially, it was described in the pleura, however, it starts out in any organ or tissue at the expense of a stromal CD34+ cell. Most of the patients are asymptomatic at the time of diagnosis. Symptoms such as cough, dyspnea, chest pain, and hypoglycemia due to production of IGF-2 have been reported (Doegge- Potter Syndrome). Others described paraneoplastic profiles are hypertrophic osteoarthropathy and in some cases galactorrhea. We report on a case of a 77 year old patient with solitary fibrous tumor in the pleura as well as symptomatic hypoglycemia. The primary treatment is surgical resection, and a longtime monitoring is necessary because recurrences can occur even after a long period of remission.