Clinical utility of sclerotherapy with a new agent for treatment of rectal prolapse in patients with risks

J Clin Gastroenterol. 2014 Apr;48(4):356-9. doi: 10.1097/MCG.0b013e318299cab8.

Abstract

Background: Perineal approaches are widely applied for the treatment of rectal prolapse. Recently, less-invasive treatments such as sclerotherapy using aluminum potassium sulfate/tannic acid (ALTA) have been introduced for internal hemorrhoids. Herein, we report the results of ALTA injection for the treatment of rectal prolapse in high-risk patients.

Methods: Between January 2009 and March 2011, we performed ALTA injection sclerosing therapy in 12 female patients with high risk for preoperative complications. Using the perineal approach, 0.5 to 1 mL of ALTA was injected into the submucosa at 30 to 60 different sites.

Results: All patients were successfully treated without any operative or postoperative morbidity. Average operation time took 35±7 (mean±SD) minutes, and average volume of ALTA injected was 39±6 mL per patient. Neither complaints of bleeding nor findings of anal stenosis were noted. A slight degree of recurrence of prolapse developed in a patient after 8 months. The patient required an additional injection to be cured.

Conclusions: ALTA injection could be administered for the treatment of rectal prolapse without any pain or complication and would be useful even for patients with risks due to preoperative complications and/or medical history.

MeSH terms

  • Aged
  • Aged, 80 and over
  • Alum Compounds / administration & dosage
  • Drug Combinations
  • Female
  • Humans
  • Injections
  • Rectal Prolapse / therapy*
  • Recurrence
  • Retrospective Studies
  • Sclerosing Solutions / administration & dosage*
  • Sclerotherapy / methods*
  • Tannins / administration & dosage
  • Treatment Outcome

Substances

  • Alum Compounds
  • Drug Combinations
  • Sclerosing Solutions
  • Tannins
  • aluminum sulfate