Breast implant associated anaplastic large cell lymphoma: a case report and reconstructive option

J Plast Reconstr Aesthet Surg. 2013 Dec;66(12):1773-6. doi: 10.1016/j.bjps.2013.04.049. Epub 2013 Jun 14.


Since 1995, the association between Anaplastic Large Cell Lymphoma (ALCL) and breast implant capsules has been of increasing concern. Up to 40 cases have been reported worldwide. The majority of cases favour an indolent course, similar to that of primary cutaneous ALCL, with a 10-year survival rate of greater than 90%. Many recommendations have been made for diagnosis, treatment and adjuvant therapy but the issue of reconstruction post capsulectomy and removal of implants has not yet been addressed. We present a case report and management option.

Keywords: ALCL; Anaplastic; Breast; Breast reconstruction; Lymphoma.

Publication types

  • Case Reports

MeSH terms

  • Adult
  • Breast Implantation
  • Breast Implants / adverse effects*
  • Breast Neoplasms / etiology*
  • Breast Neoplasms / pathology
  • Breast Neoplasms / radiotherapy
  • Breast Neoplasms / surgery*
  • Device Removal
  • Dose Fractionation, Radiation
  • Female
  • Humans
  • Lymphoma, Large-Cell, Anaplastic / etiology*
  • Lymphoma, Large-Cell, Anaplastic / pathology
  • Lymphoma, Large-Cell, Anaplastic / radiotherapy
  • Lymphoma, Large-Cell, Anaplastic / surgery*
  • Recurrence
  • Reoperation
  • Seroma / etiology
  • Seroma / pathology*
  • Silicone Gels


  • Silicone Gels