Long-term results of surgical treatment of vocal fold nodules

Laryngoscope. 2013 Aug;123(8):1926-30. doi: 10.1002/lary.23768. Epub 2013 Jun 11.

Abstract

Objectives/hypothesis: To evaluate the long-term outcome of patients with vocal fold nodules treated by surgery alone, or by a combination of surgery and voice therapy and to identify factors associated with long-term recurrent dysphonia.

Study design: Retrospective study.

Methods: All patients who had undergone surgery for vocal fold nodules in a tertiary care hospital between 1996 and 2006 were contacted. After giving their consent, they were evaluated by videostroboscopic examination of vocal fold nodules and by a subjective questionnaire including the Voice Handicap Index (VHI).

Results: Sixty-two out of 90 patients (69%) (60 women, 2 men with a mean age of 33 years) answered the questionnaire at a mean interval of 9.5 years after surgery. Recurrent dysphonia was observed in 19 patients (30%) at a mean interval of 5.2 years after surgery and new benign vocal fold lesions (nodules or Reinke's edema) were observed in 11 patients (18%). Absence of postoperative voice therapy was significantly associated with a higher recurrence rate (P = 0.02) (56% of recurrent dysphonia without voice therapy versus 22% with voice therapy).

Conclusions: Postoperative voice therapy decreases the risk of recurrence. Vocal fold nodules can recur over a period of 5 years, consequently requiring follow-up for at least 5 years in clinical practice and in future prospective studies.

Keywords: Dysphonia; Voice Handicap Index; phonosurgery; vocal fold nodules.

MeSH terms

  • Adolescent
  • Adult
  • Combined Modality Therapy / methods*
  • Dysphonia / etiology*
  • Dysphonia / surgery
  • Female
  • Humans
  • Laryngeal Neoplasms / surgery*
  • Laryngeal Neoplasms / therapy
  • Male
  • Middle Aged
  • Postoperative Complications / epidemiology*
  • Postoperative Complications / etiology
  • Retrospective Studies
  • Surveys and Questionnaires
  • Treatment Outcome
  • Vocal Cords / pathology*
  • Vocal Cords / surgery
  • Voice Disorders / diagnosis*
  • Voice Disorders / pathology
  • Voice Disorders / surgery
  • Voice Quality
  • Young Adult