[Psychomodulating activity of phenotropil in experimental hyperthyroidism]

Eksp Klin Farmakol. 2013;76(4):18-21.
[Article in Russian]

Abstract

Psychoimmunomodulating action of phenotropil has been shown on the model of experimental hyperthyroidism. It has been found that the drug (14-days i.p. injection in a dose of 25 mg/kg) is capable of restoring the cellular and humoral immunoreactivity and improve psychoemotonal state of animals by eliminating disturbances in the behavior reactions that appear as a result of the induced hyperthyroidism.

Publication types

  • English Abstract

MeSH terms

  • Animals
  • Behavior, Animal / drug effects*
  • Disease Models, Animal
  • Female
  • Hyperthyroidism* / drug therapy
  • Hyperthyroidism* / physiopathology
  • Hyperthyroidism* / psychology
  • Neuroprotective Agents / pharmacology*
  • Piracetam / analogs & derivatives*
  • Piracetam / pharmacology
  • Rats
  • Rats, Wistar

Substances

  • Neuroprotective Agents
  • 4-phenylpiracetam
  • Piracetam