TIMBAL v2: update of a database holding small molecules modulating protein-protein interactions

Database (Oxford). 2013 Jun 13;2013:bat039. doi: 10.1093/database/bat039. Print 2013.

Abstract

TIMBAL is a database holding molecules of molecular weight <1200 Daltons that modulate protein-protein interactions. Since its first release, the database has been extended to cover 50 known protein-protein interactions drug targets, including protein complexes that can be stabilized by small molecules with therapeutic effect. The resource contains 14 890 data points for 6896 distinct small molecules. UniProt codes and Protein Data Bank entries are also included. Database URL: http://www-cryst.bioc.cam.ac.uk/timbal

Publication types

  • Research Support, Non-U.S. Gov't

MeSH terms

  • Databases as Topic*
  • Databases, Protein
  • Protein Interaction Maps / drug effects*
  • Small Molecule Libraries / pharmacology*

Substances

  • Small Molecule Libraries