Neurobehavior inventory: correlation with clinical aspects and quality of life in patients with epilepsy

Epilepsy Behav. 2013 Aug;28(2):191-5. doi: 10.1016/j.yebeh.2013.05.007. Epub 2013 Jun 12.

Abstract

Fifty-five adult patients with epilepsy were evaluated, and the Neurobehavior Inventory (NBI) was administered. The relationship between the NBI data and clinical aspects and quality of life (QoL) was studied. The total NBI score was 58 ± 18.2. The domains with the highest scores were "religious conviction", "orderliness", and "sense of personal destiny". There was a significant difference in "hatred and revenge" and "religious conviction" according to the epileptic syndrome. The "physical well-being" score was higher for patients with mesial temporal lobe epilepsy with right hippocampal sclerosis than for left sclerosis (2.77 ± 1.6 × 1.57 ± 0.5, respectively, p = 0.002). The total NBI score was higher in patients with psychiatric comorbidities and with depression according to the Hamilton Depression Scale and was negatively correlated with the "emotional well-being" QOLIE score (-0.398, p = 0.005). The NBI findings showed that behavioral changes can be present in various epilepsies and that there is a complex bidirectional neurobiological relationship between epilepsy and psychiatric comorbidity, sustained by common physiopathological mechanisms.

MeSH terms

  • Adult
  • Cognition Disorders / diagnosis*
  • Cognition Disorders / etiology*
  • Electroencephalography
  • Epilepsy / complications*
  • Epilepsy / epidemiology
  • Epilepsy / psychology*
  • Female
  • Humans
  • Male
  • Mental Disorders / complications
  • Mental Disorders / epidemiology
  • Middle Aged
  • Neuropsychological Tests*
  • Quality of Life*
  • Severity of Illness Index
  • Statistics as Topic