The endocrine system comprises part of the body's communication system that links the brain to its organs and functions to control metabolism, growth development and reproduction. Control of this system is predominantly through a complex feedback system that works to maintain homeostasis. When there is disruption to an endocrine gland or to the feedback system, it can lead to endocrine disturbance. Due to the complexity of the endocrine system, diagnosis and interpretation of endocrine pathology can be challenging.