Concentrated platelet-rich plasma used in root canal revascularization: 2 case reports

Int Endod J. 2014 Jan;47(1):41-9. doi: 10.1111/iej.12144. Epub 2013 Jun 17.

Abstract

Aim: To present two case reports describing the treatment of immature teeth with necrotic pulps using concentrated platelet-rich plasma (cPRP) with 12-month clinical and radiographic follow-up.

Summary: Root canal revascularization was performed on immature permanent teeth clinically and radiographically diagnosed as requiring root canal treatment. Following disinfection of the canal space with triple antibiotic paste (1 : 1 : 1: ciprofloxacin, metronidazole and cefaclor), a tissue scaffold was created with cPRP prepared using 2-step centrifugation. The final restoration was completed with white mineral trioxide aggregate and composite resin. The patients were recalled for clinical and radiographic evaluations every 3 months. At the 12-month follow-up apical closure by narrowing of the apical foramen and convergence of the apical walls in the treated teeth was observed.

Keywords: concentrated platelet-rich plasma; immature teeth; revascularization.

Publication types

  • Case Reports

MeSH terms

  • Anti-Bacterial Agents / administration & dosage
  • Cefaclor / administration & dosage
  • Child
  • Ciprofloxacin / administration & dosage
  • Dental Pulp Cavity / blood supply*
  • Disinfection
  • Humans
  • Male
  • Metronidazole / administration & dosage
  • Neovascularization, Physiologic*
  • Platelet-Rich Plasma*

Substances

  • Anti-Bacterial Agents
  • Metronidazole
  • Ciprofloxacin
  • Cefaclor