In search of the ever-elusive positive endozepine

Neuron. 2013 Jun 19;78(6):951-2. doi: 10.1016/j.neuron.2013.06.004.

Abstract

In this issue of Neuron, Christian et al. (2013) provide functional evidence for positive endozepines (positive allosteric modulators of GABAARs) within the thalamic reticular nucleus. These molecules are encoded by the Dbi gene and modulate thalamocortical oscillations.

Publication types

  • Comment

MeSH terms

  • Animals
  • Diazepam Binding Inhibitor / physiology*
  • Female
  • Inhibitory Postsynaptic Potentials / genetics*
  • Male
  • Receptors, GABA-A / metabolism*
  • Thalamus / physiology*

Substances

  • Diazepam Binding Inhibitor
  • Receptors, GABA-A