Risks for donors in uterus transplantation

Reprod Sci. 2013 Dec;20(12):1406-15. doi: 10.1177/1933719113493517. Epub 2013 Jun 21.


Uterus transplantation (UTx) is an alternative to gestational surrogacy and adoption for patients with absolute uterine infertility. Studies have been conducted in animals, and UTx is now within the reach of clinical application in humans. Procedures in humans have been published, but many medical, ethical, and social problems and risks of UTx require discussion prior to widespread clinical application, from the perspectives of donors, recipients, families, and newborns. In this article, we summarize the burdens and risks of UTx, with a focus on donors who provide the uterus.

Keywords: donor; surrogacy; uterine infertility; uterus transplantation.

Publication types

  • Review

MeSH terms

  • Donor Selection
  • Female
  • Humans
  • Hysterectomy / adverse effects*
  • Hysterectomy / ethics
  • Infertility, Female / epidemiology
  • Infertility, Female / surgery*
  • Informed Consent
  • Living Donors
  • Mental Health
  • Risk Assessment
  • Risk Factors
  • Tissue Donors* / ethics
  • Tissue Donors* / psychology
  • Treatment Outcome
  • Uterus / transplantation*